The overarching research interest in our group is by using structural biological including electron microscopy (EM) and x-ray crystallography, biochemical, biophysical and genetical techniques to characterize protein-ligand interaction in context of cellular function to obtain insights into the mechanism of biological activity. In particular, we are now focusing on: 1) the molecular mechanism of biological nitrogen fixation; 2) the molecular mechanism of signaling transduction on cell surface; 3) the structural basis for enzymes involved in protein post-translational modification...tRNA-m1A methylation controls the infection of Magnaporth...
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